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Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune response

The importance of the macrophage in innate immunity is underscored by its secretion of an array of powerful immunoregulatory and effector molecules. We report herein that macrophage migration inhibitory factor (MIF), a product of activated macrophages, sustains macrophage survival and function by su...

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Detalles Bibliográficos
Main Authors: Mitchell, Robert A., Liao, Hong, Chesney, Jason, Fingerle-Rowson, Gunter, Baugh, John, David, John, Bucala, Richard
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC117563/
https://ncbi.nlm.nih.gov/pubmed/11756671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012511599
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