Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune response

The importance of the macrophage in innate immunity is underscored by its secretion of an array of powerful immunoregulatory and effector molecules. We report herein that macrophage migration inhibitory factor (MIF), a product of activated macrophages, sustains macrophage survival and function by su...

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Bibliographic Details
Main Authors: Mitchell, Robert A., Liao, Hong, Chesney, Jason, Fingerle-Rowson, Gunter, Baugh, John, David, John, Bucala, Richard
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC117563/
https://ncbi.nlm.nih.gov/pubmed/11756671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012511599
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