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Membrane activity of the phospholipase C-δ(1) pleckstrin homology (PH) domain

PH-PLCδ(1) [the PH domain (pleckstrin homology domain) of PLCδ(1) (phospholipase C-δ(1))] is among the best-characterized phosphoinositide-binding domains. PH-PLCδ(1) binds with high specificity to the headgroup of PtdIns(4,5)P(2), but little is known about its interfacial properties. In the present...

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Autori principali: Flesch, Frits M., Yu, Jong W., Lemmon, Mark A., Burger, Koert N. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175121/
https://ncbi.nlm.nih.gov/pubmed/15755258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041721
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