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Regeneration of the immunoglobulin heavy-chain repertoire after transient B-cell depletion with an anti-CD20 antibody

B-cell depletive therapies have beneficial effects in patients suffering from rheumatoid arthritis. Nevertheless, the role of B cells in the pathogenesis of the disease is not clear. In particular, it is not known how the regeneration of the B-cell repertoire takes place. Two patients with active rh...

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Autori principali: Rouzière, Anne-Sophie, Kneitz, Christian, Palanichamy, Arumugam, Dörner, Thomas, Tony, Hans-Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175025/
https://ncbi.nlm.nih.gov/pubmed/15987473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1731
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