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Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K(+) channel (ROMK)

The renal outer-medullary K(+) channel (ROMK; Kir1.1) mediates K(+) secretion in the renal mammalian nephron that is critical to both sodium and potassium homeostasis. The posttranscriptional expression of ROMK in the plasma membrane of cells is regulated by delivery of protein from endoplasmic reti...

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Détails bibliographiques
Auteurs principaux: O'Connell, Anthony D., Leng, Qiang, Dong, Ke, MacGregor, Gordon G., Giebisch, Gerhard, Hebert, Steven C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175014/
https://ncbi.nlm.nih.gov/pubmed/15987778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504332102
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