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Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids

We have previously shown that IFN-β inhibits hepatitis B virus (HBV) replication by noncytolytic mechanisms that either destabilize pregenomic (pg)RNA-containing capsids or prevent their assembly. Using immortalized murine hepatocyte cell lines stably transfected with a doxycycline (dox)-inducible H...

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Hlavní autoři: Wieland, Stefan F., Eustaquio, Angelina, Whitten-Bauer, Christina, Boyd, Bryan, Chisari, Francis V.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175012/
https://ncbi.nlm.nih.gov/pubmed/15994231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504273102
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