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Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection

Inducible costimulator (ICOS) has been suggested to perform an important role in T helper cell type 2 (Th2) responses, germinal center formation, and isotype switching. The role of ICOS in chronic Th2 responses was studied in a nematode model with the filarial parasite, Brugia malayi. Contrary to ex...

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Autori principali: Loke, P'ng, Zang, Xingxing, Hsuan, Lisa, Waitz, Rebecca, Locksley, Richard M., Allen, Judith E., Allison, James P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175004/
https://ncbi.nlm.nih.gov/pubmed/15994233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503961102
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