Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequences

An important step toward improving the annotation of the human genome is to identify cis-acting regulatory elements from primary DNA sequence. One approach is to compare sequences from multiple, divergent species. This approach distinguishes multispecies conserved sequences (MCS) in noncoding region...

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Detalhes bibliográficos
Main Authors: Hughes, Jim R., Cheng, Jan-Fang, Ventress, Nicki, Prabhakar, Shyam, Clark, Kevin, Anguita, Eduardo, De Gobbi, Marco, de Jong, Pieter, Rubin, Eddy, Higgs, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174996/
https://ncbi.nlm.nih.gov/pubmed/15998734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503401102
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