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Rational design of aggregation-resistant bioactive peptides: Reengineering human calcitonin
A high propensity to aggregate into intractable deposits is a common problem limiting the production and use of many peptides and proteins in a wide range of biotechnological and pharmaceutical applications. Many therapeutic polypeptides are frequently abandoned at an early stage in their developmen...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1174920/ https://ncbi.nlm.nih.gov/pubmed/16006528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501215102 |
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