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Effects of safrole and isosafrole pretreatment on N- and ring-hydroxylation of 2-acetamidofluorene by the rat and hamster

1. The effects of safrole and isosafrole pretreatment on both N- and ring-hydroxylation of 2-acetamidofluorene were studied in male rats and hamsters. 2. Isosafrole (100mg/day per kg body wt.) pretreatment of rats for 3 days did not have any effect on urinary excretion of hydroxy metabolites of 2-ac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lotlikar, Prabhakar D., Wasserman, Michael B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1972
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174239/
https://ncbi.nlm.nih.gov/pubmed/4655827
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