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Inhibitory effect of carbon monoxide on the N-and ring-hydroxylation of 2-acetamidofluorene by hamster hepatic microsomal preparations (Short Communication)

The effect of CO on N-, 3-, 5- and 7-hydroxylation of 2-acetamidofluorene by liver microsomal fractions from control and 3-methylcholanthrene-pretreated hamsters was studied. All hydroxylations were inhibited by CO, but the degree of inhibition was different for each hydroxylation. The ratios of CO...

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Detalhes bibliográficos
Main Authors: Lotlikar, Prabhakar D., Zaleski, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168511/
https://ncbi.nlm.nih.gov/pubmed/4462591
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