Characterization of protein kinase C β isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization

Retinal neovascularization is a major cause of blindness and requires the activities of several signaling pathways and multiple cytokines. Activation of protein kinase C (PKC) enhances the angiogenic process and is involved in the signaling of vascular endothelial growth factor (VEGF). We have demon...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Suzuma, Kiyoshi, Takahara, Noriko, Suzuma, Izumi, Isshiki, Keiji, Ueki, Kohjiro, Leitges, Michael, Aiello, Lloyd Paul, King, George L.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2002
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117372/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805327/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022644499
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