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Immunodetection of disease-associated mutant PrP, which accelerates disease in GSS transgenic mice
The absence of infectivity-associated, protease-resistant prion protein (PrP(Sc)) in the brains of spontaneously sick transgenic (Tg) mice overexpressing PrP linked to Gerstmann–Sträussler Scheinker syndrome, and the failure of gene-targeted mice expressing such PrP to develop disease spontaneously,...
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| Asıl Yazarlar: | , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1173157/ https://ncbi.nlm.nih.gov/pubmed/15962001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600717 |
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