TAp63α induces apoptosis by activating signaling via death receptors and mitochondria

TP63, an important epithelial developmental gene, has significant homology to p53. Unlike p53, the expression of p63 is regulated by two different promoters resulting in proteins with opposite functions: the full-length transcriptionally active TAp63 and the dominant-negative ΔNp63. We investigated...

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Detalhes bibliográficos
Main Authors: Gressner, Olav, Schilling, Tobias, Lorenz, Katja, Schulze Schleithoff, Elisa, Koch, Andreas, Schulze-Bergkamen, Henning, Maria Lena, Anna, Candi, Eleonora, Terrinoni, Alessandro, Valeria Catani, Maria, Oren, Moshe, Melino, Gerry, Krammer, Peter H, Stremmel, Wolfgang, Müller, Martina
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1173149/
https://ncbi.nlm.nih.gov/pubmed/15944736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600708
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