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ASCIZ regulates lesion-specific Rad51 focus formation and apoptosis after methylating DNA damage

Nuclear Rad51 focus formation is required for homology-directed repair of DNA double-strand breaks (DSBs), but its regulation in response to non-DSB lesions is poorly understood. Here we report a novel human SQ/TQ cluster domain-containing protein termed ASCIZ that forms Rad51-containing foci in res...

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Detalhes bibliográficos
Main Authors: McNees, Carolyn J, Conlan, Lindus A, Tenis, Nora, Heierhorst, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1173145/
https://ncbi.nlm.nih.gov/pubmed/15933716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600704
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