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ASCIZ regulates lesion-specific Rad51 focus formation and apoptosis after methylating DNA damage
Nuclear Rad51 focus formation is required for homology-directed repair of DNA double-strand breaks (DSBs), but its regulation in response to non-DSB lesions is poorly understood. Here we report a novel human SQ/TQ cluster domain-containing protein termed ASCIZ that forms Rad51-containing foci in res...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1173145/ https://ncbi.nlm.nih.gov/pubmed/15933716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600704 |
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