Unmodified Cre recombinase crosses the membrane

Site-specific recombination in genetically modified cells can be achieved by the activity of Cre recombinase from bacteriophage P1. Commonly an expression vector encoding Cre is introduced into cells; however, this can lead to undesired side-effects. Therefore, we tested whether cell-permeable Cre f...

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Библиографические подробности
Главные авторы: Will, Elke, Klump, Hannes, Heffner, Nicole, Schwieger, Maike, Schiedlmeier, Bernhard, Ostertag, Wolfram, Baum, Christopher, Stocking, Carol
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2002
Предметы:
NAR Methods Online
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC117301/
https://ncbi.nlm.nih.gov/pubmed/12060697
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