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Human OGG1 undergoes serine phosphorylation and associates with the nuclear matrix and mitotic chromatin in vivo

OGG1 is the major DNA glycosylase in human cells for removal of 7,8 dihydro-8-oxoguanine (8-oxoG), one of the most frequent endogenous base lesions formed in the DNA of aerobic organisms. During replication, 8-oxoG will frequently mispair with adenine, thus forming G:C → T:A transversions, a common...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Dantzer, Françoise, Luna, Luisa, Bjørås, Magnar, Seeberg, Erling
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117190/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12034821/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.11.2349
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