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MSL1 plays a central role in assembly of the MSL complex, essential for dosage compensation in Drosophila.
In male Drosophila, histone H4 acetylated at Lys16 is enriched on the X chromosome, and most X-linked genes are transcribed at a higher rate than in females (thus achieving dosage compensation). Five proteins, collectively called the MSLs, are required for dosage compensation and male viability. Her...
Bewaard in:
| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2000
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171786/ https://ncbi.nlm.nih.gov/pubmed/10619853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.1.144 |
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