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MSL1 plays a central role in assembly of the MSL complex, essential for dosage compensation in Drosophila.

In male Drosophila, histone H4 acetylated at Lys16 is enriched on the X chromosome, and most X-linked genes are transcribed at a higher rate than in females (thus achieving dosage compensation). Five proteins, collectively called the MSLs, are required for dosage compensation and male viability. Her...

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Dettagli Bibliografici
Autori principali: Scott, M J, Pan, L L, Cleland, S B, Knox, A L, Heinrich, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171786/
https://ncbi.nlm.nih.gov/pubmed/10619853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.1.144
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