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Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances.
The probability that two sites on a linear DNA molecule will contact each other by looping depends on DNA flexibility. Although the flexibility of naked DNA in vitro is well characterized, looping in chromatin is poorly understood. By extending existing theory, we present a single equation that desc...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
1999
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171726/ https://ncbi.nlm.nih.gov/pubmed/10581237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.23.6630 |
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