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Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme.
Processive extension of DNA in eukaryotes requires three factors to coordinate their actions. First, DNA polymerase alpha-primase synthesizes the primed site. Then replication factor C loads a proliferating cell nuclear antigen (PCNA) clamp onto the primer. Following this, DNA polymerase delta assem...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171682/ https://ncbi.nlm.nih.gov/pubmed/10545128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.21.6189 |
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