Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme.

Processive extension of DNA in eukaryotes requires three factors to coordinate their actions. First, DNA polymerase alpha-primase synthesizes the primed site. Then replication factor C loads a proliferating cell nuclear antigen (PCNA) clamp onto the primer. Following this, DNA polymerase delta assem...

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Bibliographic Details
Main Authors: Yuzhakov, A, Kelman, Z, Hurwitz, J, O'Donnell, M
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171682/
https://ncbi.nlm.nih.gov/pubmed/10545128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.21.6189
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