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A novel regulator of G protein signalling in yeast, Rgs2, downregulates glucose-activation of the cAMP pathway through direct inhibition of Gpa2.

We have characterized a novel member of the recently identified family of regulators of heterotrimeric G protein signalling (RGS) in the yeast Saccharomyces cerevisiae. The YOR107w/RGS2 gene was isolated as a multi-copy suppressor of glucose-induced loss of heat resistance in stationary phase cells....

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Autores principales: Versele, M, de Winde, J H, Thevelein, J M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171626/
https://ncbi.nlm.nih.gov/pubmed/10523302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.20.5577
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