Kelch-repeat proteins interacting with the G(α) protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase A in yeast

The cAMP–PKA pathway consists of an extracellular ligand-sensitive G protein-coupled receptor, a G protein signal transmitter, and the effector, adenylate cyclase, of which the product, cAMP, acts as an intracellular second messenger. cAMP activates PKA by dissociating the regulatory subunit from th...

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Bibliographic Details
Main Authors: Peeters, Tom, Louwet, Wendy, Geladé, Ruud, Nauwelaers, David, Thevelein, Johan M., Versele, Matthias
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559748/
https://ncbi.nlm.nih.gov/pubmed/16924114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509644103
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