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Translation driven by an eIF4G core domain in vivo.
Most eukaryotic mRNAs possess a 5' cap structure (m(7)GpppN) and a 3' poly(A) tail which promote translation initiation by binding the eukaryotic translation initiation factor (eIF)4E and the poly(A) binding protein (PABP), respectively. eIF4G can bridge between eIF4E and PABP, and-through...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171558/ https://ncbi.nlm.nih.gov/pubmed/10469664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.17.4865 |
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