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The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling.
The Drosophila misshapen (msn) gene is a member of the STE20 kinase family. We show that msn acts in the Frizzled (Fz) mediated epithelial planar polarity (EPP) signaling pathway in eyes and wings. Both msn loss- and gain-of-function result in defective ommatidial polarity and wing hair formation. G...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171540/ https://ncbi.nlm.nih.gov/pubmed/10469646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.17.4669 |
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