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SsrA-mediated peptide tagging caused by rare codons and tRNA scarcity.
SsrA RNA mediates the addition of a C-terminal peptide tag (AANDENYALAA) to bacterial proteins translated from mRNAs without in-frame stop codons. This process involves both tRNA- and mRNA-like functions of SsrA and targets the tagged proteins for degradation. By designing an SsrA variant that adds...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171532/ https://ncbi.nlm.nih.gov/pubmed/10449423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.16.4579 |
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