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Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly.

Splicing factor 1 (SF1) functions at early stages of pre-mRNA splicing and contributes to splice site recognition by interacting with the essential splicing factor U2AF65 and binding to the intron branch site. We have identified an 80 kDa substrate of cGMP-dependent protein kinase-I (PKG-I) isolated...

詳細記述

保存先:
書誌詳細
主要な著者: Wang, X, Bruderer, S, Rafi, Z, Xue, J, Milburn, P J, Krämer, A, Robinson, P J
フォーマット: Artigo
言語:Inglês
出版事項: 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171529/
https://ncbi.nlm.nih.gov/pubmed/10449420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.16.4549
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