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The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding.

Replication protein A (RPA), the eukaryote single-stranded DNA-binding protein (SSB), is a heterotrimer. The largest subunit, RPA70, which harbours the major DNA-binding activity, has two DNA-binding domains that each adopt an OB-fold. The complex of the two smaller subunits, RPA32 and RPA14, has we...

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Bibliografski detalji
Glavni autori: Bochkarev, A, Bochkareva, E, Frappier, L, Edwards, A M
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171524/
https://ncbi.nlm.nih.gov/pubmed/10449415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.16.4498
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