Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p.

Dbp5 is a DEAD-box protein essential for mRNA export from the nucleus in yeast. Here we report the isolation of a cDNA encoding human Dbp5 (hDbp5) which is 46% identical to yDbp5p. Like its yeast homologue, hDbp5 is localized within the cytoplasm and at the nuclear rim. By immunoelectron microscopy,...

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Detalhes bibliográficos
Main Authors: Schmitt, C, von Kobbe, C, Bachi, A, Panté, N, Rodrigues, J P, Boscheron, C, Rigaut, G, Wilm, M, Séraphin, B, Carmo-Fonseca, M, Izaurralde, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171509/
https://ncbi.nlm.nih.gov/pubmed/10428971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.15.4332
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