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Residues phosphorylated by TFIIH are required for E2F-1 degradation during S-phase.
The transcription factor E2F-1 plays a key role in regulating cell cycle progression. Accordingly, E2F-1 activity is itself tightly controlled by a series of transcriptional and post-transcriptional events. Here we show that the E2F-1 activation domain interacts with a kinase activity which phosphor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1999
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171504/ https://ncbi.nlm.nih.gov/pubmed/10428966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.15.4280 |
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