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An insulator element and condensed chromatin region separate the chicken beta-globin locus from an independently regulated erythroid-specific folate receptor gene.

We have identified a folate receptor gene upstream of the chicken beta-globin locus and separated from it by a 16 kbp region of silent chromatin. We find that this receptor is expressed only at a stage of erythroid differentiation (CFU-E) preceding the activation of beta-globin genes, consistent wit...

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Autors principals: Prioleau, M N, Nony, P, Simpson, M, Felsenfeld, G
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171479/
https://ncbi.nlm.nih.gov/pubmed/10406808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.14.4035
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