The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis.

The MLL gene from human chromosome 11q23 is involved in >30 different chromosomal translocations resulting in a plethora of different MLL fusion proteins. Each of these tends to associate with a specific leukaemia type, for example, MLL-AF9 is found mainly in acute myeloid leukaemia. We have stud...

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Autores principales: Dobson, C L, Warren, A J, Pannell, R, Forster, A, Lavenir, I, Corral, J, Smith, A J, Rabbitts, T H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171435/
https://ncbi.nlm.nih.gov/pubmed/10393173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.13.3564
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