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Excess beta-catenin promotes accumulation of transcriptionally active p53.
beta-catenin is a multifunctional protein, acting both as a structural component of the cell adhesion machinery and as a transducer of extracellular signals. Deregulated beta-catenin protein expression, due to mutations in the beta-catenin gene itself or in its upstream regulator, the adenomatous po...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1999
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171387/ https://ncbi.nlm.nih.gov/pubmed/10357817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.11.3054 |
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