LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2.

The Epstein-Barr virus latent membrane protein 1 (LMP1) binds tumor necrosis factor receptor (TNFR)-associated factors (TRAFs) and the TNFR-associated death domain protein (TRADD). Moreover, it induces NF-kappaB and the c-Jun N-terminal kinase 1 (JNK1) pathway. Thus, LMP1 appears to mimick the molec...

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Bibliographic Details
Main Authors: Kieser, A, Kaiser, C, Hammerschmidt, W
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171333/
https://ncbi.nlm.nih.gov/pubmed/10228165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.9.2511
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