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PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells.
The PDZ target motifs located in the C-terminal end of many receptors and ion channels mediate protein-protein interactions by binding to specific PDZ-containing proteins. These interactions are involved in the localization of surface proteins on specialized membrane domains of neuronal and epitheli...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171321/ https://ncbi.nlm.nih.gov/pubmed/10228153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.9.2384 |
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