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Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition.
The aspartate-specific caspases are critical protease effectors of programmed cell death and consequently represent important targets for apoptotic intervention. Baculovirus P35 is a potent substrate inhibitor of metazoan caspases, a property that accounts for its unique effectiveness in preventing...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171287/ https://ncbi.nlm.nih.gov/pubmed/10205157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.8.2031 |
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