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TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus.

The constitutive transport element (CTE) of the simian type D retroviruses overcomes nuclear retention and allows nuclear export of unspliced viral RNAs by recruiting TAP, a host factor which is thought to be required for export of cellular mRNAs. In this report, we show that the first 372 amino aci...

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Bibliografiske detaljer
Main Authors: Braun, I C, Rohrbach, E, Schmitt, C, Izaurralde, E
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171280/
https://ncbi.nlm.nih.gov/pubmed/10202158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.7.1953
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