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Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice.

The p38 mitogen-activated protein kinase (MAPK) pathway, like the c-Jun N-terminal kinase (JNK) MAPK pathway, is activated in response to cellular stress and inflammation and is involved in many fundamental biological processes. To study the role of the p38 MAPK pathway in vivo, we have used homolog...

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Main Authors: Lu, H T, Yang, D D, Wysk, M, Gatti, E, Mellman, I, Davis, R J, Flavell, R A
格式: Artigo
語言:Inglês
出版: 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171270/
https://ncbi.nlm.nih.gov/pubmed/10202148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.7.1845
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