The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop.

The Janus family of protein tyrosine kinases (JAKs) regulate cellular processes involved in cell growth, differentiation and transformation through their association with cytokine receptors. However, compared with other kinases, little is known about cellular regulators of the JAKs. We have recently...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yasukawa, H, Misawa, H, Sakamoto, H, Masuhara, M, Sasaki, A, Wakioka, T, Ohtsuka, S, Imaizumi, T, Matsuda, T, Ihle, J N, Yoshimura, A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1999
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171221/
https://ncbi.nlm.nih.gov/pubmed/10064597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.5.1309
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