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Translocation of ornithine decarboxylase to the surface membrane during cell activation and transformation.
Ornithine decarboxylase (ODC) is highly up-regulated in proliferating and transforming cells. Here we show that upon induction, an initial cytosolic increase of ODC is followed by translocation of a fraction of the enzyme to the surface membrane. ODC membrane translocation is mediated by a p47(phox)...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171212/ https://ncbi.nlm.nih.gov/pubmed/10064588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.5.1214 |
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