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Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding.
We recently reported the isolation and sequencing of sortilin, a new putative sorting receptor that binds receptor-associated protein (RAP). The luminal N-terminus of sortilin comprises a consensus sequence for cleavage by furin, R41WRR44, which precedes a truncation originally found in sortilin iso...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171152/ https://ncbi.nlm.nih.gov/pubmed/9927419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.3.595 |
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