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The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex.
Heparan sulfate has an important role in cell entry by foot-and-mouth disease virus (FMDV). We find that subtype O1 FMDV binds this glycosaminoglycan with a high affinity by immobilizing a specific highly abundant motif of sulfated sugars. The binding site is a shallow depression on the virion surfa...
Tallennettuna:
| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1999
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171147/ https://ncbi.nlm.nih.gov/pubmed/9927414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.3.543 |
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