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Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop.

Data from cryo-electron microscopy and X-ray crystallography have been combined to study the interactions of foot-and-mouth disease virus serotype C (FMDV-C) with a strongly neutralizing monoclonal antibody (mAb) SD6. The mAb SD6 binds to the long flexible GH-loop of viral protein 1 (VP1) which also...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hewat, E A, Verdaguer, N, Fita, I, Blakemore, W, Brookes, S, King, A, Newman, J, Domingo, E, Mateu, M G, Stuart, D I
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169753/
https://ncbi.nlm.nih.gov/pubmed/9130694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.7.1492
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