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Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation.

The molecular basis for restricted cytokine expression by T helper 1 (Th1) and T helper 2 (Th2) cells is unclear. Previous studies found that P1, an element of the interleukin 4 (IL-4) promoter that binds AP-1, is important for Th2-restricted IL-4 expression. Here we show that JunB, but not the othe...

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Detalhes bibliográficos
Main Authors: Li, B, Tournier, C, Davis, R J, Flavell, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171136/
https://ncbi.nlm.nih.gov/pubmed/9889198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.2.420
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