Thermoregulation of Shigella and Escherichia coli EIEC pathogenicity. A temperature-dependent structural transition of DNA modulates accessibility of virF promoter to transcriptional repressor H-NS.

The expression of plasmid-borne virF of Shigella encoding a transcriptional regulator of the AraC family, is required to initiate a cascade of events resulting in activation of several operons encoding invasion functions. H-NS, one of the main nucleoid-associated proteins, controls the temperature-d...

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Autores principales: Falconi, M, Colonna, B, Prosseda, G, Micheli, G, Gualerzi, C O
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171051/
https://ncbi.nlm.nih.gov/pubmed/9843508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.23.7033
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