Crosslinking the EcoRV restriction endonuclease across the DNA-binding site reveals transient intermediates and conformational changes of the enzyme during DNA binding and catalytic turnover.

Míreanna Comhchosúla

• Linear diffusion of the restriction endonuclease EcoRV on DNA is essential for the in vivo function of the enzyme.
  le: Jeltsch, A, et al.
  Foilsithe: (1996)
• Role of thymidine residues in DNA recognition by the EcoRI and EcoRV restriction endonucleases.
  le: Fliess, A, et al.
  Foilsithe: (1986)
• Solution parameters modulating DNA binding specificity of the restriction endonuclease EcoRV
  le: Sidorova, Nina Y., et al.
  Foilsithe: (2011)
• Substrate-assisted catalysis in the cleavage of DNA by the EcoRI and EcoRV restriction enzymes.
  le: Jeltsch, A, et al.
  Foilsithe: (1993)
• Introduction of asymmetry in the naturally symmetric restriction endonuclease EcoRV to investigate intersubunit communication in the homodimeric protein.
  le: Stahl, F, et al.
  Foilsithe: (1996)