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Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7.

Interferon (IFN) genes are among the earliest transcriptional responses to virus infection of mammalian cells. Although the regulation of the IFNbeta gene has been well characterized, the induction of the large family of IFNalpha genes has remained obscure. We report that the IFNalpha genes can be d...

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Bibliographic Details
Main Authors: Marié, I, Durbin, J E, Levy, D E
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171011/
https://ncbi.nlm.nih.gov/pubmed/9822609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.22.6660
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