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Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.
The major heat shock protein, Hsp70, is an effective inhibitor of apoptosis. To study its mechanism of action, we created tumor cell lines with altered Hsp70 levels. The expression levels of Hsp70 in the cells obtained correlated well with their survival following treatments with tumor necrosis fact...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170939/ https://ncbi.nlm.nih.gov/pubmed/9799222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.21.6124 |
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