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Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.

The major heat shock protein, Hsp70, is an effective inhibitor of apoptosis. To study its mechanism of action, we created tumor cell lines with altered Hsp70 levels. The expression levels of Hsp70 in the cells obtained correlated well with their survival following treatments with tumor necrosis fact...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jäättelä, M, Wissing, D, Kokholm, K, Kallunki, T, Egeblad, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170939/
https://ncbi.nlm.nih.gov/pubmed/9799222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.21.6124
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