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Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.

The amphiphysins are brain-enriched proteins, implicated in clathrin-mediated endocytosis, that interact with dynamin through their SH3 domains. To elucidate the nature of this interaction, we have solved the crystal structure of the amphiphysin-2 (Amph2) SH3 domain to 2.2 A. The structure possesses...

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Hlavní autoři: Owen, D J, Wigge, P, Vallis, Y, Moore, J D, Evans, P R, McMahon, H T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170855/
https://ncbi.nlm.nih.gov/pubmed/9736607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.18.5273
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